A 45-year-old patient with a history of HIV/AIDS and mildly impaired renal function presents with signs/symptoms of acute gouty arthritis. His antiretroviral regimen includes a strong inhibitor of CYP3A4. Which one of the following medications is effective in the treatment of the pain and inflammation of acute gouty flare but contraindicated in this patient?
A. Abatacept
B. Colchicine
C. Febuxostat
D. Prednisone
E. Probenecid
Answer: B
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Biomechanics
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- A 56-year-old female with a known history of seropositive rheumatoid arthritis maintained on etanercept injections presents complaining of right knee pain and swelling for two days. She has been in good health otherwise and denies fevers and chills. She reports stiffness in the right knee that lasts for longer than 1 hour. Her other joints are doing well. You perform an arthrocentesis and remove 30cc of clear fluid. You send the sample to the lab, and 24 hours later no organisms are seen. The patient follows up later that day. The best course of management for this patient is:
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